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Cavolin-1 ligand WL47

Chemical Structure : Cavolin-1 ligand WL47

CAS No.:

Cavolin-1 ligand WL47 (Peptide WL47)

Catalog No.: PC-24721Not For Human Use, Lab Use Only.

Cavolin-1 ligand WL47 is a peptide, high-affinity, selective disrupter / inhibitor of caveolin-1 (CAV) oligomerization with ITC KD of 23 nM, 7500-fold improved affinity compared to its T20 parent ligand.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cavolin-1 ligand WL47 is a peptide, high-affinity, selective disrupter / inhibitor of caveolin-1 (CAV) oligomerization with ITC KD of 23 nM, 7500-fold improved affinity compared to its T20 parent ligand.

Physicochemical Properties

M.Wt 1942.32
Formula C82H131N24F3O29S4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Sequence: Lys-Leu-Arg-Met-Trp-Ser-Cys-Cys-Ser-Trp-Met-Arg-Leu-Lys (TFA salt)

References

1. Gilliam AJ, et al. J Med Chem. 2016 Apr 28;59(8):4019-25.

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