Ciliogenesis inhibitor Nao-3 | Ciliogenesis inhibitor

Chemical Structure : Ciliogenesis inhibitor Nao-3

Ciliogenesis inhibitor Nao-3 (Naonedin-3)

Catalog No.: PC-25807Not For Human Use, Lab Use Only.

Ciliogenesis inhibitor Nao-3 (Naonedin-3) is specific small-molecule inhibitor of ciliogenesis, represses primary ciliogenesis and induces the death of chemoresistant ciliated stem-like cells.

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Biological Activity

Ciliogenesis inhibitor Nao-3 (Naonedin-3) is specific small-molecule inhibitor of ciliogenesis, represses primary ciliogenesis and induces the death of chemoresistant ciliated stem-like cells.
Nao-3 significantly represses cilium assembly in multiple patient samples in a dose-dependent manner（IC50=47.1 nM）

Physicochemical Properties

M.Wt	409.87
Formula	C23H20ClNO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(6-chloro-1,4-dimethyl-9H-carbazol-3-yl)(4-hydroxy-3,5-dimethoxyphenyl)methanone

References

1. Tessier CE, et al. EMBO Mol Med. 2025 Oct;17(10):2536-2561.

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Ciliogenesis inhibitor Nao-3 (Naonedin-3)

Biological Activity

Physicochemical Properties

References

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