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Chemical Structure : ClpP agonist TR-57
Catalog No.: PC-49802Not For Human Use, Lab Use Only.
ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM.
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ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM.
TR-57 exhibits the growth inhibition with a ClpP-dependent manner in both MDA-MB-231 and HEK293 T-REx cells.
TR-27 induces ClpP-dependent proteolysis on the N-terminome of the proteome in MDA-MB-231 cells.
| M.Wt | 419.91 | |
| Formula | C24H22ClN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mark F Mabanglo, et al. Structure. 2023 Feb 2;31(2):185-200.e10.
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