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Chemical Structure : Compound 797780-71-3
Catalog No.: PC-22173Not For Human Use, Lab Use Only.
Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway.
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Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway.
Compound 797780-71-3 demonstrates potent binding affinity in both noncovalent and covalent docking for DJ-1.
Compound 797780-71-3 (20 uM) completely inhibits the levels of β-catenin and the phosphorylation of GSK3β in ACHN cells.
| M.Wt | 301.73 | |
| Formula | C16H12ClNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yanyu Ma, et al. Future Med Chem. 2024 Apr;16(7):665-677.
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