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Compound A5

Chemical Structure : Compound A5

CAS No.: 938071-78-4

Compound A5 (Compound 5431942)

Catalog No.: PC-70260Not For Human Use, Lab Use Only.

A small molecule that specifically inhibits the clathrin adaptor complex AP-1-dependent traffic, does not significantly affect other pathways through the trans-Golgi network (TGN).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A small molecule that specifically inhibits the clathrin adaptor complex AP-1-dependent traffic, does not significantly affect other pathways through the trans-Golgi network (TGN); specifically alters the distribution of AP-1 in mammalian cells, inhibits traffic between the TGN and endosomes.

Physicochemical Properties

M.Wt 308.85
Formula C17H25ClN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-1-(4-(4-(2-methylbut-2-en-1-yl)piperazin-1-yl)phenyl)ethan-1-one hydrochloride

References

1. Duncan MC, et al. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6235-40.

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