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Cromoglicic acid

Chemical Structure : Cromoglicic acid

CAS No.: 16110-51-3

Cromoglicic acid (Cromolyn;FPL-670)

Catalog No.: PC-61795Not For Human Use, Lab Use Only.

Cromoglicic acid is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Cromoglicic acid is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells; also inhibits chloride channels, and binds S100P to block the interaction between S100P and RAGE.

Psoriasis

Phase 3 Clinical

Physicochemical Properties

M.Wt 468.367
Formula C23H16O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid

References

1. Heinke S, et al. Br J Pharmacol. 1995 Aug;115(8):1393-8.

2. Zur E, et al. Int J Pharm Compd. 2012 Sep-Oct;16(5):386-93.

3. Penumutchu SR, et al. Biochem Biophys Res Commun. 2014 Nov 21;454(3):404-9.

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