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Chemical Structure D211
CAS No.: 1971075-99-6
Catalog No.: PC-60140Not For Human Use, Lab Use Only.
A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs).
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| 25 mg | Get quote | ||
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| 1 g | Get quote |
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A novel potent DNA-intercalating payload dimer (PBD dimer) payload for antibody-drug conjugates (ADCs); displays picomolar potency against AML cancer cell lines.
| M.Wt | 656.739 | |
| Formula | C39H36N4O6 | |
| CAS No. | 1971075-99-6 | |
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| Chemical Name |
(6aS,6a'S)-3,3'-(propane-1,3-diylbis(oxy))bis(2-methoxy-7,12-dihydrobenzo[5,6][1,4]diazepino[1,2-b]isoquinolin-14(6aH)-one) |
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1. Sean W. Smith, et al. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00436
