Catalog No.: PC-70081Not For Human Use, Lab Use Only.
DBCO-NHS ester is an amine-reactive NHS ester as ADC linker that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
DBCO-NHS ester is an amine-reactive NHS ester as ADC linker that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
DBCO-NHS ester is a click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
Physicochemical Properties
M.Wt
430.45
Formula
C25H22N2O5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Dibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es
References
1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.
