DBCO-NHS ester 2
DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry; is useful in strain-promoted copper-free azide-alkyne cycloaddition reactions; used in DNA-assisted protein analysis such as proximity ligation and extention assays, antibody drug conjugates.
Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
A heterobifunctional cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity; a useful protective group in antibody drug conjugates.
A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
A Cu(I)-stabilizing ligand that shows high activity in accelerating the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC); BTTAA-Cu(I) catalyst is the optimal choice for cell surface azide-alkyne ligation, mediates CuAAC and copper-free click chemistry.
A cathepsin cleavable ADC peptide linker.
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