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Chemical Structure : DCP1-3
Catalog No.: PC-72732Not For Human Use, Lab Use Only.
DCP1-3 is a novel allosteric ligand of the angiotensin receptor AT1R, displays NAM potency on AngIV with IC50 of 0.29 uM.
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DCP1-3 is a novel allosteric ligand of the angiotensin receptor AT1R, displays NAM potency on AngIV with IC50 of 0.29 uM.
DCP1-3 reduces AngII-induced contraction in renal and iliac arteries in mice.
DCP1-3 inhibits IgG binding to HEK-AT1R cells with IC50 of 2.9 nM.
DCP1-3 reverses PAM effect of the IgG on the agonist-induced calcium response.
| M.Wt | 396.459 | |
| Formula | C20H29FN2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Singh KD, et al. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33):e2019126118.
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