Chemical Structure : DC_AC50
CAS No.: 497061-48-0
Catalog No.: PC-61245Not For Human Use, Lab Use Only.
DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation.
DC_AC50 induces cellular reactive oxygen species (ROS) accumulation and reduces cellular ATP production, induces mitochondria defects and decreases lipid biosynthesis through AMPK activation.
DC_AC50 suppresses tumour growth effectively without affecting normal tissues in mice.
| M.Wt | 424.264 | |
| Formula | C17H12BrF2N3OS | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-amino-N-(2-bromo-4,6-difluorophenyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide |
|
1. Wang J, et al. Nat Chem. 2015 Dec;7(12):968-79.
2. Karginova O, et al. Mol Cancer Ther. 2019 Mar 1. pii: molcanther.0667.2018.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright