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DFPM

Chemical Structure : DFPM

CAS No.: 301338-95-4

DFPM

Catalog No.: PC-61225Not For Human Use, Lab Use Only.

A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.

Physicochemical Properties

M.Wt 340.262
Formula C16H15Cl2NOS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[5-(3,4-dichlorophenyl)furan-2-yl]-piperidine-1-ylmethanethione

References

1. Kim TH, et al. Curr Biol. 2011 Jun 7;21(11):990-7.

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