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Chemical Structure : DHPCC-9
Catalog No.: PC-38739Not For Human Use, Lab Use Only.
DHPCC-9 is a selective Pim kinase inhibitor, inhibits Pim-1-dependent survival of cytokine-deprived myeloid cells (IC50=4-6 uM).
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DHPCC-9 is a selective Pim kinase inhibitor, inhibits Pim-1-dependent survival of cytokine-deprived myeloid cells (IC50=4-6 uM).
DHPCC-9 represses intracellular phosphorylation of Bad by Pim kinases.
DHPCC-9 decreases migration of prostate cancer cells without affecting Pim protein levels or cell viability, also reduces migration of squamocellular carcinoma cells.
DHPCC-9 drastically decreases tumor volumes as well as the metastatic capacity in prostate cancer xenografts.
| M.Wt | 234.258 | |
| Formula | C15H10N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Santio NM, et al. Mol Cancer. 2010 Oct 19;9:279.
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