DIBDO

Chemical Structure : DIBDO

Catalog No.: PC-27435Not For Human Use, Lab Use Only.

DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells.

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Biological Activity

DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells.

Physicochemical Properties

M.Wt	339.90
Formula	C4H6I2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2,3-diiodobut-2-ene-1,4-diol

References

1. Zhao D, et al. Adv Sci (Weinh). 2026 Jul 23:e76655.

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DIBDO

Biological Activity

Physicochemical Properties

References

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