DK1-04 | SIRT5 inhibitor | Probechem Biochemicals

Chemical Structure : DK1-04

Catalog No.: PC-38160Not For Human Use, Lab Use Only.

DK1-04 is a potent, selective, cell-permeable small-molecule SIRT5 inhibitor with IC50 of 0.34 uM, shows no inhibition on SIRT1-3/6 at 83 uM.

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Biological Activity

DK1-04 is a potent, selective, cell-permeable small-molecule SIRT5 inhibitor with IC50 of 0.34 uM, shows no inhibition on SIRT1-3/6 at 83 uM.

M.Wt	615.746
Formula	C30H41N5O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5S,8S)-8-((3-hydroxyphenyl)carbamoyl)-5-isobutyl-3,6-dioxo-1-phenyl-14-thioxo-2-oxa-4,7,13,15-tetraazaoctadecan-18-oic acid

1. Yashira L Negrón Abril, et al. Oncogene. 2021 Mar;40(9):1644-1658.