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DK1-04

Chemical Structure : DK1-04

CAS No.: 2760692-55-3

DK1-04 (SIRT5 inhibitor DK1-04)

Catalog No.: PC-38160Not For Human Use, Lab Use Only.

DK1-04 is a potent, selective, cell-permeable small-molecule SIRT5 inhibitor with IC50 of 0.34 uM, shows no inhibition on SIRT1-3/6 at 83 uM..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DK1-04 is a potent, selective, cell-permeable small-molecule SIRT5 inhibitor with IC50 of 0.34 uM, shows no inhibition on SIRT1-3/6 at 83 uM.

Physicochemical Properties

M.Wt 615.746
Formula C30H41N5O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5S,8S)-8-((3-hydroxyphenyl)carbamoyl)-5-isobutyl-3,6-dioxo-1-phenyl-14-thioxo-2-oxa-4,7,13,15-tetraazaoctadecan-18-oic acid

References

1. Yashira L Negrón Abril, et al. Oncogene. 2021 Mar;40(9):1644-1658.

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