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Chemical Structure : DP308
Catalog No.: PC-21491Not For Human Use, Lab Use Only.
DP308 is a novel and effective 53BP1 tandem Tudor domain (TTD) inhibitor, disrupts the binding between 53BP1 and H4K20me2 peptide with IC50 of 1.69 uM.
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DP308 is a novel and effective 53BP1 tandem Tudor domain (TTD) inhibitor, disrupts the binding between 53BP1 and H4K20me2 peptide with IC50 of 1.69 uM.
DP308 directly binds to 53BP1-TTD protein with binding affinity (Kd) of about 2.7 μM in SPR assays.
| M.Wt | 349.43 | |
| Formula | C21H23N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yanli Sun, et al. Bioorg Med Chem. 2021 Mar 15:34:116054.
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