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Chemical Structure : DPM-1001
Catalog No.: PC-62543Not For Human Use, Lab Use Only.
DPM-1001 is a potent, selective, orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B with IC50 of 100 nM, also chelates copper, which enhanced its potency as a PTP1B inhibitor.
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DPM-1001 is a potent, selective, orally bioavailable inhibitor of the protein-tyrosine phosphatase PTP1B with IC50 of 100 nM, also chelates copper, which enhanced its potency as a PTP1B inhibitor.
DPM-1001 displays anti-diabetic properties associated with enhanced signaling through insulin and leptin receptors in animal models of diet-induced obesity.
| M.Wt | 567.859 | |
| Formula | C35H57N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Krishnan N, et al. J Biol Chem. 2018 Feb 2;293(5):1517-1525.
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