DS69910557 | hPTHR1 antagonist | Probechem Biochemicals

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Chemical Structure : DS69910557

DS69910557 (DS 69910557)

Catalog No.: PC-38658Not For Human Use, Lab Use Only.

DS69910557 is a highly potent, selective orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DS69910557 is a highly potent, selective orally available human parathyroid hormone receptor 1 (hPTHR1) antagonist.
DS69910557 demonstrated in vivo potency to decrease the plasma calcium concentration in rats upon oral administration.

Physicochemical Properties

M.Wt	611.539
Formula	C32H33Cl2FN4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1r,4r)-4-(((1-(4-(2,9-dichloro-5,5-dimethyl-6-oxo-5,6-dihydro-7H-benzo[b]pyrido[3,2-d]azepin-7-yl)phenyl)-3-fluoroazetidin-3-yl)methyl)amino)cyclohexane-1-carboxylic acid

References

1. Yoshikazu Arai, et al. Bioorg Med Chem. 2022 Jun 15;64:116763.

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DS69910557 (DS 69910557)

Biological Activity

Physicochemical Properties

References

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