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Chemical Structure : DZ-2384
Catalog No.: PC-35304Not For Human Use, Lab Use Only.
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.
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DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types; binds the vinca domain of tubulin, DZ-2384 has potent antitumor activity as a single agent and in combination with gemcitabine both in vitro and in vivo, enhances gemcitabine activity in mouse models of pancreatic cancer.
| M.Wt | 645.677 | |
| Formula | C34H36FN5O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ding H, et al. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4818-22.
2. Wieczorek M, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra159.
3. Bernier C, et al. Anticancer Drugs. 2018 Jun 22. doi: 10.1097/CAD.0000000000000653.
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