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Chemical Structure : Daclatasvir dihydrochloride
CAS No.: 1009119-65-6
Catalog No.: PC-42603Not For Human Use, Lab Use Only.
A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $60 | In stock | |
| 50 mg | $120 | In stock | |
| 100 mg | $152 | In stock |
Bulk size, bulk discount!
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A potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons; exhibits picomolar EC(50) towards replicons expressing a broad range of HCV genotypes and the JFH-1 genotype 2a infectious virus in cell culture.
HCV Infection
Approved
| M.Wt | 811.7969 | |
| Formula | C40H52Cl2N8O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 56 mg/mL |
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| Chemical Name/SMILES |
Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester, hydrochloride (1:2) |
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1. Gao M, et al. Nature. 2010 May 6;465(7294):96-100.
2. Lemm JA, et al. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.
3. Fridell RA, et al. Antimicrob Agents Chemother. 2010 Sep;54(9):3641-50.
4. Fridell RA, et al. J Virol. 2011 Jul;85(14):7312-20.
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