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Chemical Structure : Deoxygedunin
Catalog No.: PC-70344Not For Human Use, Lab Use Only.
A naturally occurring tetranortriterpenoid that has been found to act as a potent, selective, small-molecule agonist of TrkB with Kd of 1.4 uM.
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A naturally occurring tetranortriterpenoid that has been found to act as a potent, selective, small-molecule agonist of TrkB with Kd of 1.4 uM; activates TrkB in mouse brain in a BDNF-independent way, prevents the degeneration of vestibular ganglion in BDNF -/- pups, and produces TrkB-dependent neurotrophic and neuroprotective effects in mice and enhances learning processes.
| M.Wt | 466.566 | |
| Formula | C28H34O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. English AW, et al. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16217-22.
2. Jang SW, et al. PLoS One. 2010 Jul 13;5(7):e11528.
3. Nie S, et al. Neuropharmacology. 2015 Dec;99:448-58.
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