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Chemical Structure : Desmethyl dabrafenib
Catalog No.: PC-35415Not For Human Use, Lab Use Only.
Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo..
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Desmethyl dabrafenib (GSK2167542, Dabrafenib metabolite M8) is the desmethyl- metabolic byproduct of Dabrafenib, ameliorates developmental pathologies of Kabuki Syndrome in vivo.
| M.Wt | 505.534 | |
| Formula | C22H18F3N5O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bershas DA, et al. Drug Metab Dispos. 2013 Dec;41(12):2215-24.
2. Ouellet D, et al. J Clin Pharmacol. 2014 Jun;54(6):696-706.
3. Suttle AB, et al. J Clin Pharmacol. 2015 Apr;55(4):392-400.
4. Tsai IC, et al. Sci Rep. 2018 Jul 17;8(1):10779.
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