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Dichlorcyclizine

Chemical Structure : Dichlorcyclizine

CAS No.: 1784701-16-1

Dichlorcyclizine (DCCZ)

Catalog No.: PC-72892Not For Human Use, Lab Use Only.

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection with EC50 of 9.92 and 4.53 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 9.92 and 4.53 uM, respectively.

Physicochemical Properties

M.Wt 349.299
Formula C19H22Cl2N2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(bis(4-chlorophenyl)methyl)-4-ethylpiperazine

References

1. Christopher D Ma, et al. Nat Microbiol. 2020 Dec;5(12):1532-1541.

2. Park SB, et al. mBio. 2022 Jan 11;13(1):e0323821.

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