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Chemical Structure : Dickkopf inhibitor IIIC3
Catalog No.: PC-62022Not For Human Use, Lab Use Only.
NCI8642 (Gallocyanine, Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist Dickkopf with EC50 of 5 uM for reversing DKK1 CM-mediated Wnt inhibition.
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NCI8642 (Gallocyanine, Dickkopf inhibitor IIIC3) is a small-molecule inhibitor of Wnt antagonist Dickkopf with EC50 of 5 uM for reversing DKK1 CM-mediated Wnt inhibition.
NCI8642 (Gallocyanine, Dickkopf inhibitor IIIC3) inhibits the binding of DKK1-alkaline phosphatase (AP) to HEK293 cells expressing the wild-type LRP5 or LRP5 mutant with IC50 of 3 uM.
NCI8642 (Gallocyanine, Dickkopf inhibitor IIIC3) reduces basal blood-glucose concentrations and improves glucose tolerance in mice.
| M.Wt | 300.27 | |
| Formula | C15H12N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li X, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11402-7.
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