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Dorzolamide hydrochloride

Chemical Structure : Dorzolamide hydrochloride

CAS No.: 130693-82-2

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Dorzolamide hydrochloride (L671152)

Catalog No.: PC-24456Not For Human Use, Lab Use Only.

Dorzolamide hydrochloride (L671152) is a potent, selective carbonic anhydrase II (CA II) inhibitor with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively.

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25 mg $58 In stock
50 mg $88 In stock
100 mg $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Dorzolamide hydrochloride (L671152) is a potent, selective carbonic anhydrase II (CA II) inhibitor with IC50 values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively.

Physicochemical Properties

M.Wt 360.89
Formula C10H17ClN2O4S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride

References

1. Belal M Ali, et al. Naunyn Schmiedebergs Arch Pharmacol. 2015 Dec;388(12):1271-82.

2. J Biollaz, et al. Eur J Clin Pharmacol. 1995;47(5):455-60.

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