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Chemical Structure : Edoxaban
CAS No.: 480449-70-5
Catalog No.: PC-42502Not For Human Use, Lab Use Only.
A potent and orally active Factor Xa inhibitor with Ki of 0.561 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $208 | In stock | |
| 50 mg | $724 | In stock | |
| 100 mg | $968 | In stock |
Bulk size, bulk discount!
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A potent and orally active Factor Xa inhibitor with Ki of 0.561 nM; also inhibits prothrombinase (Ki=2.98 nM), weakly inhibits thrombin and FIXa (Ki=6.0 uM, and 41.7 uM); exhibits >10,000-fold selectivity for Fxa over FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin and chymotrypsin; inhibits thrombus formation in rat and rabbit thrombosis models.
Thrombosis
Approved
| M.Wt | 548.0575 | |
| Formula | C24H30ClN7O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]- |
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1. Furugohri T, et al. J Thromb Haemost. 2008 Sep;6(9):1542-9.
2. Furugohri T, et al. Eur J Pharmacol. 2012 Jul 5;686(1-3):74-80.
3. Morishima Y, et al. Thromb Res. 2013 Jan;131(1):59-63.
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