Chemical Structure : Elamipretide acetate
CAS No.:
1334953-95-5
Elamipretide acetate
(SS-31, MTP 131 acetate, Bendavia)
Catalog No. : PC-27242Not For Human Use, Lab Use Only.
Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2724201
Biological Activity
Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
Physicochemical Properties
M.Wt
699.85
Formula
C34H53N9O7
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-6-amino-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-((R)-2-amino-5-guanidinopentanamido)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)hexanamide acetate
References
1. Thomas DA, et al. J Am Soc Nephrol. 2007 Jan;18(1):213-22.
2. Zhao K, et al. Biochem Pharmacol. 2005 Dec 5;70(12):1796-806.
3. Mizuguchi Y, et al. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1545-53.
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