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Chemical Structure : Eliglustat
CAS No.: 491833-29-5
Catalog No.: PC-49448Not For Human Use, Lab Use Only.
Eliglustat (GENZ 112638)Eliglustat (GENZ 112638) is a ceramide analog and an orally bioavailable inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase) with IC50 of 20 nM in free-cell assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | $488 | In stock | |
| 1 g | Get quote |
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Eliglustat (GENZ 112638)Eliglustat (GENZ 112638) is a ceramide analog and an orally bioavailable inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase) with IC50 of 20 nM in free-cell assays.
Eliglustat (GENZ 112638) decrease the production of glycosphingolipids (GSLs) including glucosylceramide, also known as glucocerebroside.
Eliglustat (GENZ 112638) decreases the production of glucosylceramide and other GSLs, which have important roles in various diseases and cellular processes, including immune processes and functions.
| M.Wt | 404.551 | |
| Formula | C23H36N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide |
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1. Jianxun Du, et al. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127209.
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