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Elobixibat

Chemical Structure : Elobixibat

CAS No.: 439087-18-0

Elobixibat (A-3309;AZD-7806;AJG-533)

Catalog No.: PC-61407Not For Human Use, Lab Use Only.

An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

An orally available, potent and selective ileal bile acid transporter (IBAT) inhibitor for the treatment of constipation.

Other Indication

Phase 2 Clinical

Physicochemical Properties

M.Wt 695.89
Formula C36H45N3O7S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Glycine, (2R)-N-[[[3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycyl- (9CI)

References

1. Chey WD, et al. Gastroenterol. 2014 May;109(5):782.

2. Wong BS, et al. Expert Opin Investig Drugs. 2013 Feb;22(2):277-84.

3. Wong BS, et al. Am J Gastroenterol. 2011 Dec;106(12):2154-64.

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