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Enexasogaol

Chemical Structure : Enexasogaol

CAS No.: 23513-13-5

Enexasogaol (6-Shogaol)

Catalog No.: PC-61375Not For Human Use, Lab Use Only.

A pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects; attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ; inhibits TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes; also induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism.

Physicochemical Properties

M.Wt 276.376
Formula C17H24O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one

References

1. Isa Y, et al. Biochem Biophys Res Commun. 2008 Aug 29;373(3):429-34.

2. Pan MH, et al. Mol Nutr Food Res. 2008 May;52(5):527-37.

3. Chen CY, et al. J Agric Food Chem. 2007 Feb 7;55(3):948-54.

4. Han Q,et al. Oncotarget. 2017 Jun 27;8(26):42001-42006.

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