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Chemical Structure : Epothilone A
CAS No.: 152044-53-6
Catalog No.: PC-20928Not For Human Use, Lab Use Only.
Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $218 | In stock | |
| 25 mg | $388 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
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Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM.
Epothilone A (Epo A) shows highly cytotoxic effect (IC50=0.05 μM) in vitro of human T-24 bladder carcinoma cell line.
| M.Wt | 493.66 | |
| Formula | C26H39NO6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C[C@]3([H])O[C@]3([H])CCC[C@H](C)[C@H](O)[C@@H](C)C1=O |
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1. Kowalski RJ, et al. J Biol Chem. 1997 Jan 24;272(4):2534-41.
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