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Chemical Structure : Eribaxaban
Catalog No.: PC-60954Not For Human Use, Lab Use Only.
A potent, selective and orally efficacious factor Xa (FXa) inhibitor with IC50 of 0.32 nM.
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A potent, selective and orally efficacious factor Xa (FXa) inhibitor with IC50 of 0.32 nM; displays >1,000-fold selectivity over a series of related serine proteases (thrombin, activated protein C, plasmin, tissue plasminogen activator and trypsin); potently inhibits thrombosis and shows potential for s for the treatment and prevention of thrombotic disorders.
Thrombosis
Phase 2 Discontinued
| M.Wt | 484.912 | |
| Formula | C24H22ClFN4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kohrt JT, et al. Chem Biol Drug Des. 2007 Aug;70(2):100-12.
2. McBane RD 2nd, et al. Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):413-8.
3. Karnicki K, et al. Thromb Haemost. 2008 Apr;99(4):759-66.
4. Cohen AT, et al. J Thromb Haemost. 2013 Aug;11(8):1503-10.
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