Chemical Structure : Evans Blue
CAS No.: 314-13-6
Catalog No.: PC-24513Not For Human Use, Lab Use Only.
Evans Blue is a selective small-molecule inhibitor of CaMKII-alpha (CaMKII-α) with IC50 of 197.1 nM, also is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).
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|---|---|---|---|
| 100 mg | $38 | In stock | |
| 250 mg | $58 | In stock | |
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Evans Blue is a selective small-molecule inhibitor of CaMKII-alpha (CaMKII-α) with IC50 of 197.1 nM, also is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).
Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor.
Evans Blue has a strong affinity towards serum albumin, as a high molecular weight protein tracer.
Evans Blue is also used to study BBB (blood-brain barrier) permeability.
| M.Wt | 960.79 | |
| Formula | C34H24N6Na4O14S4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Sodium 6,6'-((3,3'-dimethyl-[1,1'-biphenyl]-4,4'-diyl)bis(diazene-2,1-diyl))bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate) |
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1. Tian J, et al. Cancer Sci. 2025 Apr 4. doi: 10.1111/cas.70051.
2. Linpeng Yao, et al. Contrast Media Mol Imaging. 2018 Apr 22:2018:7628037.
3. Anatol Manaenko, et al. J Neurosci Methods. 2011 Feb 15;195(2):206-10.

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