F35-303

Chemical Structure : F35-303

Catalog No.: PC-28412Not For Human Use, Lab Use Only.

F35-303 is a small molecule inhibitor of BEX4-XRCC5 interaction with IC50 of 2.39 uM in Huh6 cells, exhibits binding affinity for XRCC5 with SPR KD of 0.751 uM, suppresses NHEJ repair activity and reduces HB cells cell viability, inhibits cisplatin resistance.

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Biological Activity

Physicochemical Properties

M.Wt	303.34
Formula	C16H18FN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-[(3S)-3-amino-1-pyrrolidinyl]-3-[5-(4-fluorophenyl)-2-oxazolyl]-1-propanone

References

1. Yan Z, et al. Pharmacol Res. 2026 Sep 30;233:109658.

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F35-303

Biological Activity

Physicochemical Properties

References

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