You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-F83236
F83236

Chemical Structure : F83236

CAS No.:

F83236 (F 83236)

Catalog No.: PC-20735Not For Human Use, Lab Use Only.

F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
200 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets.
F83236 has potent and specific inhibitory activity against CypA, CypB, and CypD.
F83236 prevents mPTP opening in mitochondria from primary human and mouse hepatocytes and protected mice from liver ischemia-reperfusion injury upon binding catalytic and gatekeeper pockets of CypD.

Physicochemical Properties

M.Wt 633.61
Formula C32H33BrN4O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(NCC1=CC2=C(NCCC2)C=C1)NC(C3=CC(Br)=CC=C3OC)C(N4C(C5=C6C(C=CS6)=CC=C5)CCC4)=O

References

1. Jens Van Bael, et al. Int J Mol Sci. 2023 Apr 12;24(8):7163.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: