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Chemical Structure : FPPS-IN-11
CAS No.: 1250273-31-4
Catalog No.: PC-38605Not For Human Use, Lab Use Only.
FPPS-IN-11 is a potent, allosteric, non-bisphosphonate farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 200 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote |
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FPPS-IN-11 is a potent, allosteric, non-bisphosphonate farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 200 nM.
FPPS-IN-11 displayed similar potencies in biochemical assays to the most potent bisphosphonate, zoledronic acid (IC50=130 nM), and similar to or higher than those of all other bisphosphonates used clinically, such as risedronate, ibandronate, alendronate and pamidronate (IC50 = 150 nM, 340 nM, 850 nM, 950 nM, respectively).
| M.Wt | 269.256 | |
| Formula | C15H11NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid |
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1. Wolfgang Jahnke, et al. Nat Chem Biol. 2010 Sep;6(9):660-6.
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