Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : FPR1 agonist fMLF
CAS No.: 59880-97-6
Catalog No.: PC-72083Not For Human Use, Lab Use Only.
FPR1 agonist fMLF is a potent, selective formylpeptide receptor-1 (FPR1) agonist with EC50 of 80 nM in calcium flux, Ki of 38 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $228 | In stock | |
| 100 mg | $528 | In stock | |
| 250 mg | $798 | In stock | |
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
FPR1 agonist fMLF is a potent, selective formylpeptide receptor-1 (FPR1) agonist with EC50 of 80 nM in calcium flux, Ki of 38 nM.
fMLF activates mononuclear phagocytes to cellular activation, which is characterized by cellular polarization, chemotaxis, and release of proteolytic enzymes.
fMLF induces contractions in isolated guinea pig jejunum (EC50 = 11 nM), proximal colon (EC50 = 3.5 nM), and distal colon (EC50 = 2.2 nM).
fMLF induces neurotransmitter release from enteric motor neurons in vitro.
| M.Wt | 437.6 | |
| Formula | C21H31N3O5S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-formyl-L-methionyl-L-leucyl-L-phenylalanine |
|
1. Lind S, et al. J Leukoc Biol. 2021 Jun;109(6):1105-1120.
2. Hu Y, et al. Chembiochem. 2014 Nov 3;15(16):2420-6.
3. Partida-Sánchez S, et al. J Immunol. 2004 Feb 1;172(3):1896-906.
4. Salamah MF, et al. J Thromb Haemost. 2019 Jul;17(7):1120-1133.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
