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FQI2

Chemical Structure : FQI2

CAS No.: 1373209-41-6

FQI2 (FQI 2)

Catalog No.: PC-62025Not For Human Use, Lab Use Only.

FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

FQI2 is a small-molecule inhibitor of transcription factor LSF with IC50 of 0.71 uM; inhibits LSF DNA-binding activity both in vitro, also exhibits antiproliferative activity in multiple cell lines, NIH 3T3, HeLa S3, and A549 cells with GI50 of 0.71, 0.40, and 1.6 uM, respectively; rapidly induces cell death in QGY-7703 liver cancer cell lines.

Physicochemical Properties

M.Wt 309.321
Formula C18H15NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-(2-ethoxyphenyl)-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

References

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