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Chemical Structure : Famitinib
Catalog No.: PC-62597Not For Human Use, Lab Use Only.
Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.
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Famitinib (SHR1020) is a structural analogue of sunitinib, novel and potent multi-targeted RTK inhibitor, including c-Kit, VEGFR2/3, PDGFRβ, FLT-1/3 receptor and c-RET.
Famitinib (SHR1020) demonstrates the higher potency in tumour growth inhibition in human tumour xenograft models compared with sunitinib.
| M.Wt | 410.493 | |
| Formula | C23H27FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xie C, et al. Br J Pharmacol. 2013 Apr;168(7):1687-706.
2. Zhang W, et al. Chin Med J (Engl). 2013 Nov;126(22):4277-81.
3. Zhou A, et al. Cancer Chemother Pharmacol. 2013 Nov;72(5):1043-53.
4. Ge S, et al. Oncol Lett. 2016 Sep;12(3):1763-1768.
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