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Chemical Structure : Fasudil
CAS No.: 103745-39-7
Catalog No.: PC-42541Not For Human Use, Lab Use Only.
A potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 200 mg | $56 | In stock | |
| 500 mg | $88 | In stock |
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A potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 μM in cell-free assays, respectively; exhibits vasodilator actions by inhibition of 5-hydroxytryptamine, noradrenaline, histamine, angiotensin, and dopamine induced spiral strips contraction.
| M.Wt | 291.3687 | |
| Formula | C14H17N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]- |
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1. Ono-Saito N, et al.1999 May-Jun;82(2-3):123-31.
2. Asano T, et al. J Pharmacol Exp Ther. 1987 Jun;241(3):1033-40.
3. Asano T, et al. Br J Pharmacol. 1989 Dec;98(4):1091-100.
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