Fexofenadine | H1 receptor antagonist, ADAM17 inhibitor

Chemical Structure : Fexofenadine

CAS No.: 83799-24-0

Fexofenadine (MDL-16455, Terfenadine carboxylate)

Catalog No.: PC-26776Not For Human Use, Lab Use Only.

Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist, also binds and inhibits the catalytic activity of human ADAM17, shows anti-inflammatory effects.

Packing	Price	Stock
25 mg	$58	In stock
50 mg	$88	In stock
100 mg	$128	In stock
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Biological Activity

Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist, also binds and inhibits the catalytic activity of human ADAM17, shows anti-inflammatory effects.

Physicochemical Properties

M.Wt	501.67
Formula	C32H39NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid

References

1. Shahid Puthiyottil, et al. Biochem Pharmacol. 2026 May 10:118041.

2. Watanabe N, et al. Int Immunopharmacol. 2004 Mar;4(3):367-75.

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Fexofenadine (MDL-16455, Terfenadine carboxylate)

Biological Activity

Physicochemical Properties

References

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