| Cat. No. |
Product Name |
Information |
| PC-47094 |
RGH-235
H3R antagonist
|
RGH-235 is a potent, selective, and orally active H3 receptor antagonist/inverse agonist with high affinity (Ki=3.0-9.2 nM, depending on species), without affinity to H1, H2 or H4 receptors. |
| PC-36072 |
VUF15000
Histamine H3 agonist
|
VUF15000 (VUF-15000) is the first photoswitchable GPCR Histamine H3 receptor agonist (pKi=8.42), displays >300-fold selective for hH3R over hH1R and hH2R. |
| PC-36071 |
NLX-204
5-HT1A agonist
|
NLX-204 (NLX204) is a potent, selective, ERK1/2 phosphorylation-preferring serotonin 5-HT1A receptor agonist with pEC50 of 9.37. |
| PC-35982 |
SUVN-G3031 free base
Histamine H3 inverse agonist
|
SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R). |
| PC-35981 |
SUVN-G3031
Histamine H3 inverse agonist
|
SUVN-G3031 (SUVN-G 3031) is a potent, selective, orally active histamine H3 receptor (H3R) inverse agonist with Ki of 8.73 nM (hH3R). |
| PC-35223 |
Clobenpropit dihydrobromide
Histamine H3 inverse agonist
|
Clobenpropit (VUF-9153) is a highly potent histamine H3 antagonist/inverse agonist with pA2 value of 9.93, also displays partial agonist activity at H4 receptors. |
| PC-63422 |
UR-PI376
Histamine H4 agonist
|
UR-PI376 is a potent, selective histamine H4 receptor (hH4R) agonist with pEC50 of 7.47, shows negligible hH1R and hH2R activities and significant selectivity over the hH3R.. |
| PC-63420 |
A-943931
Histamine H4 antagonist
|
A-943931 is a potent, selective antagonist of histamine H4 receptor (H4R) with binding pKi of 8.33 and 8.42 for hH4 and rH4, respectively. |
| PC-63417 |
JNJ-40279486
Histamine H4 antagonist
|
JNJ-40279486 is a potent, selective histamine H4 receptor antagonist with Ki of 9.4 nM (hH4), demonstrates acceptable pharmacokinetic profile and efficacy in mouse model of inflammation.. |
| PC-63400 |
JNJ-18038683
|
JNJ-18038683 is a potent, selective 5-HT7 receptor antagonist with pKi of 8.19 and 8.20 for rat and human 5-HT7 in cell-based assays. |
| PC-63035 |
MK-0249
Histamine H3 antagonist
|
MK-0249 is a potent, selective and orally active histamine H3 receptor antagonist, with an IC50 of 1.7 nM for human H3. |
| PC-61615 |
Irdabisant
H3 receptor antagonist
|
Irdabisant (CEP-26401) is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
