Fluoxakalner

Chemical Structure : Fluoxakalner

Catalog No.: PC-27997Not For Human Use, Lab Use Only.

Fluoxakalner is a potent, selective Kv7.2/7.3 (KCNQ2/3) channel opener / activator with EC50 of 0.36 uM and 38.45 ± 5.80 mV leftward shift (ΔV1/2) in channel activation, produces robust antinociception in mouse pain models.

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Biological Activity

Fluoxakalner is a potent, selective Kv7.2/7.3 (KCNQ2/3) channel opener / activator with EC50 of 0.36 uM and 38.45 ± 5.80 mV leftward shift (ΔV1/2) in channel activation, produces robust antinociception in mouse pain models.

Physicochemical Properties

M.Wt	363.43
Formula	C23H22FNO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-{4-[(4-fluorobenzyl)oxy]-2,6-dimethylphenyl}-2-phenylacetamide

References

1. Wei Xiang, et al. Bioorg Chem. 2026 Sep 15:180:110099.

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Fluoxakalner

Biological Activity

Physicochemical Properties

References

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