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Fmoc-Val-Cit-PAB

Chemical Structure Fmoc-Val-Cit-PAB

CAS No.: 159858-22-7

Fmoc-Val-Cit-PAB

Catalog No.: PC-45601Not For Human Use, Lab Use Only.

Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.

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25 mg $185 In stock
100 mg $385 In stock
250 mg $585 In stock
1 g $1180 In stock
5 g Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Fmoc-Val-Cit-PAB is a peptide prodrug linker for antibody-drug conjugates (ADCs), a cleavable ADC linker for antibody-drug conjugate.

Physicochemical Properties

M.Wt 601.6927
Formula C33H39N5O6
CAS No. 159858-22-7
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 1 Month
Shipping
Solubility

DMSO: ≥ 123.75 mg/mL

Chemical Name

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-

Clinical Information

References

1. Doronina SO, et al. Nat Biotechnol. 2003 Jul;21(7):778-84.

2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.

3. Beckley NS, et al. Bioconjug Chem. 2013 Oct 16;24(10):1674-83.

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