GDC-4379 | JAK inhibitor | Probechem Biochemicals

Chemical Structure : GDC-4379

GDC-4379 (GDC4379)

Catalog No.: PC-21215Not For Human Use, Lab Use Only.

GDC-4379 is a potent, selective and inhaled JAK inhibitor with IC50 of 2 nM and 36 nM for JAK1 and JAK2 respectively, reduces FeNO and peripheral biomarkers of inflammation.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

GDC-4379 is a potent, selective and inhaled JAK inhibitor with IC50 of 2 nM and 36 nM for JAK1 and JAK2 respectively, reduces FeNO and peripheral biomarkers of inflammation.

Physicochemical Properties

M.Wt	489.87
Formula	C21H18ClF2N7O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-(dimethylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-

References

1. Chen H, et al. Pulm Pharmacol Ther. 2022 Aug;75:102133.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

GDC-4379 (GDC4379)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.