Catalog No.: PC-28623Not For Human Use, Lab Use Only.
GMQ hydrochloride (2-guanidine-4-methylquinazoline hydrochloride) is a specific agonist for ASIC3 homomers, causes persistent ASIC3 channel activation at neutral pH, acilitates ASIC3 activation (EC50=67 μM) without affecting the ASIC1a, 1b and 2a channels.
GMQ hydrochloride (2-guanidine-4-methylquinazoline hydrochloride) is a specific agonist for ASIC3 homomers, causes persistent ASIC3 channel activation at neutral pH, acilitates ASIC3 activation (EC50=67 μM) without affecting the ASIC1a, 1b and 2a channels. GMQ activates sensory neurons and causes pain-related behaviors in an ASIC3-dependent manner. GMQ acts on ASIC3 channels in a different way from protons. GMQ causes pain-related behaviors via ASIC3 channels.
