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GNE-987

Chemical Structure : GNE-987

CAS No.: 2417371-71-0

GNE-987 (GNE987)

Catalog No.: PC-72911Not For Human Use, Lab Use Only.

GNE-987 (GNE987) is a highly potent chimeric BET degrader, exhibits BRD4 degradation activity in EOL-1 AML cell line with DC50 of 30 pM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GNE-987 (GNE987) is a highly potent chimeric BET degrader, exhibits BRD4 degradation activity in EOL-1 AML cell line with DC50 of 30 pM.

Physicochemical Properties

M.Wt 1096.32
Formula C56H67F2N9O8S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

Chemical Name/SMILES

References

1. Thomas H Pillow, et al. ChemMedChem. 2020 Jan 7;15(1):17-25.

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