Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : GNF-6702
Catalog No.: PC-60315Not For Human Use, Lab Use Only.
GNF-6702 (GNF6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
GNF-6702 (GNF6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM; displays no inhibitory effect on caspase-like and the trypsin-like activities (>10 uM); does not inhibit the mammalian proteasome or growth of mammalian cells, and is well-tolerated in mice; clears parasites in mouse models of kinetoplastid infections.
| M.Wt | 429.406 | |
| Formula | C22H16FN7O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Khare S, et al. Nature. 2016 Sep 8;537(7619):229-233.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
