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Chemical Structure : GNF-9228
Catalog No.: PC-47060Not For Human Use, Lab Use Only.
GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation.
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GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation.
GNF-9228 stimulates insulin secretion in rat and human islets.
GNF-9228 protects 832/13 cells from ER stress and cytokine-induced cytotoxicity.
Rat islet cell proliferation induced by GNF-9228 is not inhibited by overexpression of DYRK1A.
| M.Wt | 294.310 | |
| Formula | C17H14N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hans E Hohmeier, et al. PLoS One. 2020 Mar 16;15(3):e0224344.
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