GPR83 agonist CPD27

Chemical Structure : GPR83 agonist CPD27

Catalog No.: PC-26013ANot For Human Use, Lab Use Only.

GPR83 agonist CPD27 is a potent, selective small molecule GPR83 agonist with binding IC50 of 0.1 nM, and EC50 of 0.8 nM for [35S]GTPγS binding to membranes from CHO cells expressing mouse GPR83.

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Biological Activity

GPR83 agonist CPD27 is a potent, selective small molecule GPR83 agonist with binding IC50 of 0.1 nM, and EC50 of 0.8 nM for [35S]GTPγS binding to membranes from CHO cells expressing mouse GPR83.

Physicochemical Properties

M.Wt	376.42
Formula	C21H20N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl (4-(3-(1H-pyrazol-1-yl)phenyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)carbamate

References

1. Gomes I, et al. Mol Pharmacol. 2025 Nov 24;108(1):100092.

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